Skip to main content
Western Kentucky University

Media Relations

Stress experienced by men alters sperm and affects children

Stress as a pre-adolescent or adult leaves a lasting impression on a dad's sperm that gives his kids a blunted reaction to stress, U.S. researchers say.

Study leader Tracy L. Bale of the Perelman School of Medicine and the School of Veterinary Medicine at the University of Pennsylvania in Philadelphia said the findings point to a never-before-seen link to stress-related diseases such as anxiety and depression passed from father to child.

The study involved male mice exposed to six weeks of chronic stress, before breeding, either throughout puberty or only in adulthood. Examples of stress include sudden move to another cage, predator odor such as fox urine, noise, or a foreign object in the cage.

Male mice are ideal for such an experiment because they do not participate in offspring rearing, meaning any external factors outside of germ-cell formation are essentially eliminated, Bale said.

The study, published in the Journal of Neuroscience, found offspring from paternal stress groups displayed significantly blunted levels of the stress hormone corticosterone -- in humans, it's cortisol -- in response to stress.

This stress pathway dysregulation -- when reactivity to stress is either heightened or reduced -- is a sign an organism doesn't have the ability to respond appropriately to a changing environment and as a result, their stress response becomes irregular, which can lead to stress-related disorders, Bale said.

"It didn't matter if dads were going through puberty or in adulthood when stressed before they mated," Bale said in a statement. "We've shown here for the first time that stress can produce long-term changes to sperm that reprogram the offspring hypothalamic-pituitary-adrenal axis, a region of the brain that governs responses to stress."



Original link: http://www.upi.com/Health_News/2013/06/14/Stress-experienced-by-men-alters-sperm-and-affects-children/UPI-52111371257322/#ixzz2WTojYY1I

Categories
All News  Now Viewing Category: All
School of Journalism & Broadcasting
CEBS
Media Relations
Academic Affairs
Augenstein Alumni Center
Instruments of American Excellence
Transportation
Emergency Preparedness
Police
Department of Music
Department of Theatre & Dance
Library News
Office of Sustainability
Office of International Programs
Office of Research
Ogden News
PCAL
WKU Greeks News
WKU Parent and Family Weekend
Parent's Association
Student Activities and Organizations
Scholarships Student Financial Assistance
Student Government Association News
Van Meter Auditorium
Teaching News
Study Abroad
Student Research Council
Student Employment
WKU Joint Admissions
International Student Office
Human Resources News
Cultural Enhancement Series
CHHS News
The Confucius Institute
Campus Activities Board
GFCB
WellU
The Carol Martin Gatton Academy of Mathematics and Science in Kentucky
Development and Alumni Relations
Downing Student Union
Health Services
Hardin Planetarium
News from The Center for Gifted Studies
Student Financial Assistance
Downing Museum
Etown & Fort Knox
Facilities
Employee Wellness
Latest Headlines
Featured Articles
WKU hosting FIRST« LEGO« League Qualifying Tournament Nov. 22
Topper Tank Awards $1,500 to Student Entrepreneurs
Dr. Susan Baum Presents at the 2014 Twice-Exceptional Seminar

Forty parents, educators, counselors, and administrators came to Bowling Green November 5 to hear a leading authority on twice-exceptional education at the 2014 Twice-Exceptional (2e) Learners Seminar.

Note: documents in Portable Document Format (PDF) require Adobe Acrobat Reader 5.0 or higher to view,
download Adobe Acrobat Reader.

Note: documents in Excel format (XLS) require Microsoft Viewer,
download excel.

Note: documents in Word format (DOC) require Microsoft Viewer,
download word.

Note: documents in Powerpoint format (PPT) require Microsoft Viewer,
download powerpoint.

Note: documents in Quicktime Movie format [MOV] require Apple Quicktime,
download quicktime.

 
 Last Modified 9/24/14